Medications for Stimulant Use Disorders

You can call us at (323) 522-2218 to talk confidentially with a member of our care team. Tell us your story and let’s explore your options.

While there is no FDA-approved medication to treat methamphetamine or cocaine use disorder like there is for opioids, research has shown there are medications that may help reduce your cravings and treat common co-occuring conditions.

The following is a list of medications that our doctors have found to be helpful and effective in providing a support system to reduce drug usage and feel better. Get in contact with us to learn more and discuss your options.

MedicationSummaryHow it works
NaltrexoneNaltrexone is an opioid antagonist and is commonly used to help treat a number of different substance use disorders.Naltrexone is often prescribed to help people manage drug and alcohol cravings and avoid relapse. Research studies have shown that it can reduce some of the effects of stimulants, which in turn may help people reduce their drug usage.
BupropionBupropion is an antidepressant.Research has shown that it reduces both the high associated with drug usage as well as trigger-induced cravings. In combination with Naltrexone, studies have shown that it helps drive lower drug usage and better treatment program participation for some individuals.
MirtazapineMirtazapine is an antidepressant.Research studies have demonstrated that mirtazapine can increase abstinence and reduce risky behaviors associated with methamphetamine usage.
BuspironeBuspirone is an anxiolytic agent used to treat anxiety. Unlike other medications used to treat anxiety, it has few side effects and is not addictive.Many individuals with stimulant use disorder suffer from anxiety, which Buspirone helps address. Additionally, it blocks dopamine receptors in the brain, which can in turn reduce the high associated with drug use. Early studies have suggested this may be effective in helping people manage cravings, but more research remains to be done.
RamelteonRamelteon is a sedative used to treat insomnia.Many individuals suffering from stimulant use disorder have insomnia or struggle to develop consistent sleep habits. Ramelteon can help make you drowsy and encourage sleep.
GabapentinGabapentin is an anticonvulsant used to help reduce seizures and treat other conditions, such as restless legs syndrome (RLS).While the exact mechanism of Gabapentin is not fully understood, it may help reduce excitatory brain signaling. It is most often used to treat alcohol use disorder, but some research has shown modest effectiveness in managing detox from other substances as well.

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